Healthy Natural Detox:
Natural Detox - Phase I and Phase II
To truly understand detoxification and what will be effective, one must comprehend the steps, which occur primarily within the liver (and to some extent the intestinal lining...less in other cells) and supplement the needed co-factors. So to properly address a healthy, natural mercury detox, one has to up-regulate liver cleansing and liver detox processes.
The liver essentially detoxifies in two phases, each one preparing the offending agent for expulsion by the liver into the feces by basically making the toxin more and more water soluble.
Phase I - The toxin is made more water-soluble and more biochemically reactive. This is accomplished by a group of enzymes (about 150 of them) collectively called "cytochrome P450’s. In fact, at this stage the toxin is "opened" up by these enzymes so it will bind or conjugate with an acceptable substrate (an 'add-on' made probably from carbon, hydrogen, oxygen and often
sulphur..maybe nitrogen) in Phase II, forming a complex the liver will recognize as foreign and excrete via the bowels. There are a lot of free radicals produced in this process and we must have enough antioxidant present to offset it or else other negative implications to health will result.
As a matter of fact, sometimes in this part of the detox process, the toxin can actually be temporarily even MORE toxic as it's being opened.
To support Phase I activity, I will add Oxygenics (more on the liver supplements later) depending on the patient’s current health. The more chemically sensitive the patient is - the more antioxidant protection they need. It must however be added gradually, starting at only 1-2 capsules per day.
One of the roles of bile is to help excretion of these toxins…but fibre in the gut is needed to bind the bile, so a low fiber diet hinders this process.
Phase II - Conjugation
In phase II, the now very reactive toxin is bound to another molecule, in the case of mercury-glutathione- to form an excretable complex. There are a total of six compounds that toxins can bind to at this point, but glutathione is of most importance in this discussion on mercury.
Drainage Products Detoxification Products
Continue to Section 4 - Glutathione-Essential Mercury Detox Molecule
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